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Ablation of the Sam68 gene impairs fertilità and gonadotropin-dependent follicle development. |
Human Molecular Genetics (in press). |
| Valacca, C., Bonomi, S., Buratti, E., Pedrotti, S., Baralle, F.E., Sette, C., Ghigna, C., Biamonti, G. |
Sam68 regulates EMT through alternative splicing-activated nonsense-mediated mRNA decay of the SF2/ASF proto-oncogene. |
Journal of Cell Biology 191, 87-99. |
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Spinal Muscular Atrophy: a novel player joins the battle for SMN2 exon 7 splicing. |
Cell Cycle 9, 3874-9. |
| Busà, R., Sette, C. |
An emerging role for nuclear RNA-mediated responses to genotoxic stress. |
RNA Biology 17, 7(4). |
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The splicing regulator Sam68 binds to a novel exonic splicing silencer and functions in SMN2 alternative splicing in spinal muscular atrophy. |
EMBO Journal 29, 1235-47. |
| Busà, R., Geremia, R., Sette, C. |
Genotoxic stress causes the accumulation of the splicing regulator Sam68 in nuclear foci of transcriptionally active chromatin. |
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Alternative splicing of the proto-oncogene CCND1 is regulated by Sam68 in human prostate cancer. |
Cancer Research 70, 229-39. |
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Role of RNA-binding proteins in mammalian spermatogenesis. |
International Journal of Andrology 33, 2-12. |
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DBASS3 and DBASS5: databases of aberrant 3’ and 5’ splice sites. |
Nucleic Acids Research [Epub ahead of print]. |
| Valacca, C., Bonomi, S., Buratti, E., Pedrotti, S., Baralle, F.E., Sette, C., Ghigna, C., Biamonti, G. |
Sam68 regulates EMT through alternative splicing-activated NMD of the SF2/ASF proto-oncogene. |
Journal of Cell Biology 191(1), 87-99. |
| Änkö, M-L., Morales, L., Henry, I., Beyer, A. and Neugebauer, K.M. |
Global analysis reveals SRp20- and SRp75-specific mRNPs in cycling and neural cells. |
Nature Structural and Molecular Biology 17, 962-70. |
| Pabis, M., Neufeld, N., Shav-Tal, Y. and Neugebauer, K.M. |
Expression and dynamic localization of an alternative isoform of the nuclear cap-binding complex subunit CBP20. |
Nucleus 1, 412-421. |
| Huranová, M., Ivani, I., Benda, A., Poser, I., Brody, Y., Hof, M., Shav-Tal, Y., Neugebauer, K.M. and Stanek, D. |
Differential interaction of snRNPs with pre-mRNA reveals splicing kinetics in living cells. |
Journal of Cell Biology 191, 75-86. |
| Pelisch, F., Gerez, J., Druker, J., Schor, I.E., Muñoz, M.J., Risso, G., Petrillo, E., Westman, B.J., Lamond, A.I., Arzt, E., and Srebrow, A. |
The serine/arginine-rich protein SF2/ASF regulates protein sumoylation. |
Proceedings of the National Academy of Science USA, [Epub ahead of print]. |
| Llorian, M., Schwartz, S., Clark, T.A., Hollander, D., Tan, L-Y., Spellman, R., Gordon, A., Schweitzer, A.C., de la Grange, P., Ast, G., Smith, C.W.J. |
Position-dependent alternative splicing activity revealed by global profiling of alternative splicing events regulated by PTB. |
Nature Structural & Molecular Biology, [Epub ahead of print]. |
| Ghigna, C., De Toledo, M., Bonomi, S., Valacca, C., Gallo, S., Apicella, M., Eperon, I., Tazi, J. and Biamonti, G. |
Pro-metastatic splicing of Ron proto-oncogene mRNA can be reversed: Therapeutic potential of bifunctional oligonucleotides and indole derivatives. |
RNA Biology 7(4), [Epub ahead of print]. |
| Cherny, D., Gooding, C., Eperon, G.E., Coelho, M.B., Bagshaw, C.R., Smith, C.W.J. and Eperon, I.C. |
Stoichiometry of a regulatory splicing complex revealed by single molecule analyses. |
EMBO Journal 29, 2161-2172. |
| Nlend Nlend, R., Meyer, K. and Schümperli, D. |
Repair of pre-mRNA splicing: Prospects for a therapy for Spinal Muscular Atrophy. |
RNA Biology 7(4), [Epub ahead of print]. |
| Ittig, D., Luisier, S., Weiler, J., Schümperli, D. and Leumann, C.J. |
Improving gene silencing of siRNAs via tricyclo-DNA modification. |
Artificial DNA 1, 1-8. |
| Strzelecka, M., Trowitzsch, S., Weber, G., Lührmann, R., Oates, A.C. and Neugebauer, K.M. |
Coilin-dependent snRNP assembly is essential for zebrafish embryogenesis. |
Nature Structural and Molecular Biology 17, 403–409. |
| Strzelecka, M., Oates, A.C. and Neugebauer, K.M. |
Dynamic control of Cajal body number in zebrafish embryogenesis. |
Nucleus 1, 96-108. |
| Dreumont, N., Bourgeois, C.F., Lejeune, F., Liu, Y., Ehrmann, I.E., Elliott, D.J., Stévenin, J. |
Human RBMY regulates germline-specific splicing events by modulating the function of the serine/arginine-rich proteins 9G8 and Tra2-{beta}. |
Journal of Cell Science 123, 40-50. |
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