Special Issue of Journal of Nucleic Acids on Alternative Splicing and Cancer

The main focus of this special issue will be on the
mechanisms involved in splicing alteration in cancer and on
new proofs of the involvement of alteration of alternative
splicing in different steps and aspects of cancer initiation
and progression. Moreover, papers dealing with new cancer
therapeutic targets and strategies relying on splicing would
be of great interest. Main topics include, but are not limited
• Genetics
• Large-scale analysis of alternative splicing
• Alternative promoters and polyadenylation sites
• Trans-splicing
• Functions of splicing isoforms
• Splicing alterations of oncogenes and tumor suppressor
• Splicing factors as multifunctional proteins
• Mechanisms of splicing alteration
• Splicing factor expression
• Signaling pathways and oncoproteins/oncosuppressors
affecting alternative splicing
• Coupling transcription and splicing
• Therapeutic targets and strategies relying on splicing

Please, see a Call-for-Paper for more information.

Before submission authors should carefully read over the
journal’s Author Guidelines, which are located at here. Prospective authors should submit an electronic copy of their complete manuscript through the journal Manuscript Tracking System according to the following timetable:

Manuscript Due May 1, 2011
First Round of Reviews August 1, 2011
Publication Date November 1, 2011

Lead Guest Editor
Didier Auboeuf, Institut National de la Sante et de la
Recherche (INSERM); Centre Léon Bérard, Lyon, France;

Guest Editors
Maria Carmo-Fonseca, Institute of Molecular Medicine,
Faculty of Medicine, Lisbon, Portugal;

Juan Valcarcel, Institució Catalana de Recerca i Estudis
Avançats (ICREA); Centre de Regulacio Genomica,
Barcelona, Spain;

Giuseppe Biamonti, Institute of Molecular Genetics,
Italian National Research Council, Rome, Italy;