Inter Disciplinary Focus Meeting 'Mouse models for alternative splicing'

The goal of the IFM 'Mouse models for alternative splicing' will be to review the state-of-the-art in the generation of mouse models for addressing biological problems and provide examples of how these have been successfully applied to studies of alternative splicing.

Program:

9.00-9.45

Klaus Rajewsky
Harvard Medical School, Boston, MA
Facts, Artifacts and Interpretations in Conditional Gene Targeting Experiments

9.55-10.40

Bill Skarnes
Sanger Institute, Cambridge
High-throughput gene targeting in mouse ES cells: a post-genomic approach

10.50-11.15 Coffee break

11.15-12.00

Frank Grosveld
Erasmus University, Rotterdam
Long Range Genomic Interactions

12.10-12.55

Xiang-Dong Fu
University of California in San Diego, San Diego, CA
Function of the splicing machinery in vivo: Novel insights from developing cellular and animal models

13.05-14.30 Lunch

14.30-15.15

Maurice Swanson
University of Florida, Gainesville, FL
Mechanisms of RNA-mediated Disease: Lessons from Mouse Models

15.25-16.10

Mariano A. García-Blanco
Center for RNA Biology, Duke University Medical Center, Durham, NC
ALTERNATIVE SPLICING AND EPITHELIAL-MESENCHYMAL TRANSITIONS

16.20-16.45 Coffee break

16.45-17.30

Andrés Muro
ICGEB, Trieste
Tales from a mouse model: New insights into form and function of fibronectin splice variants

17.40-18.25

Glauco Tocchini-Valentini
Instituto di Biología Cellulare, Rome
Cis- and trans-RNA splicing catalyzed by tRNA endonucleases

18.35 end of workshop

More details are available on the IFM website.
For information, please contact Juan Valcárcel.